Degenertive Joint disease
Osteoarthriris
- Normal articular cartilage
- Chondrocyte
- Extracellular matrix
- Pathophysiology
- Cause of Osteoarthriris
- Primary OA
- Secondary OA
- Trauma
- infection
- repetitive overload
- Pathology
- Progressive cartilage destruction
- Sclerosis of the surrounding bone
- subarticular cyst formation
- Capsular fibrosis
- Clinical presentation
- Natural history
- Symptoms : Pain Swelling, Deformity, Loss of motion
- Sign: Joint swelling ,Joint deformity, Local tenderness, Crepitation, Limited movement, Muscle wasting, Instability
Investigation
- Plain film
- joint space narrowing
- subchrondal sclerosis
- subchondral cyst
- MRI
Differential Diagnosis
- Joint infection
- Crystal induced arthritis
- Lesion from remote areas
- Inflammatory arthropathy
- Neuropathic arthropathy
Treatment
- Supportive treatment
- Relieve pain
- Maintain joint mobility
- Muscle strengthening
- Modify daily activities
- Viscosupplementation
Surgical treatment
- Cartilage repair
- Joint debridement
- Corrective osteotomy
- Joint replacement (arthroplasty)